CORDIS Project
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This project focuses on understanding the role of macrophage CD40 signaling in atherosclerosis, a major cause of cardiovascular diseases. It aims to explore potential therapeutic strategies targeting this pathway to reduce inflammation and disease progression.
Atherosclerosis, the underlying cause of the majority of cardiovascular diseases (CVD), is a lipid driven, inflammatory disease of the large arteries.
Despite a 25% relative risk reduction achieved by lipid-lowering treatment, the vast majority of atherosclerosis-induced CVD risk remains unaddressed.
Therefore, characterizing mediators of the inflammatory aspect of atherosclerosis is a widely recognized scientific goal with great therapeutic implications.Co-stimulatory molecules are key players…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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Netherlands, Amsterdam
Type: Research institute
Activity type: Research Organisations
SME: No
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