CORDIS Project
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This project investigates the role of cyclic di-GMP in microbial physiology, focusing on identifying and characterizing its binding receptors in Salmonella typhimurium. The research aims to enhance understanding of bacterial adaptation and regulation mechanisms.
Nucleotide signaling plays an important role in the adjustment of microbial physiology and metabolism.
These signaling systems are involved in the regulation of all physiological processes including biofilm formation, virulence, environmental survival, and phage defense.
One of the most prominent nucleotide-based second messenger molecules is the ubiquitous second messenger cyclic di-GMP.
Cyclic di‐GMP synthesizing and hydrolyzing proteins, GGDEF and EAL domain proteins, respectively, are widely…
KAROLINSKA INSTITUTET
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