CORDIS Project
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This project investigates how variations in Cadherin proteins influence cell adhesion and tissue development in multicellular organisms. By analyzing these proteins across different species and testing their effects in zebrafish embryos, the research aims to reveal fundamental principles of cell contact dynamics and mo…
As a zygote develops into a multicellular organism, cell contacts are crucial to shape the embryo.
Metazoans utilize Cadherin proteins for adhesion in which the extracellular domains establish cell contacts and intracellular domains mechanically couple the cytoskeleton.
The nature of the cell contact is critical for defining cell shapes and the physical properties of the tissue.
While the intracellular domain is highly conserved, the architecture of their extracellular domains varies widely acro…
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
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