CORDIS Project
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This project investigates a newly discovered bacterial communication system in Streptococcus agalactiae, focusing on its role in regulating virulence factors. By understanding this mechanism, the project aims to identify new targets for reducing the bacterium's pathogenicity, which is crucial for protecting vulnerable…
Quorum sensing (QS) is a bacterial cell-to-cell communication process to control gene expression at population level.
Recently, a new QS mechanism was described in streptococci.
It involves a transcriptional regulator of the Rgg family and a small hydrophobic peptide (SHP), acting as a signaling molecule.
The interaction between SHP and Rgg allows Rgg to control the expression of its target genes.
One rgg/shp locus is present in Streptococcus agalactiae (Group B Streptococci), a commensal bacter…
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
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