CORDIS Project
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This project investigates the use of genetically engineered bacteria as living vectors for gene therapy. It aims to create a small, wall-less bacterium that can be manipulated to deliver therapeutic proteins directly into human cells, potentially treating genetic diseases.
The idea of harnessing living organisms for treating human diseases is not new but, so far, the majority of the living vectors used in human therapy are viruses which have the disadvantage of the limited number of genes and networks that can contain.
Bacteria allow the cloning of complex networks and the possibility of making a large plethora of compounds, naturally or through careful redesign.
One of the main limitations for the use of bacteria to treat human diseases is their complexity, the e…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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