CORDIS Project
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The project explores the mechanisms of cell fate decisions during stem cell differentiation by developing advanced microfluidic tools. It aims to understand how mechanical signals influence these choices, integrating biology with innovative biotechnology.
The evolution from a stem cell to differentiated progeny underpins tissue development and homeostasis, which are driven by a multitude of cell fate choices.
The transitions underlying these choices are not well understood.
There are a number of challenges that must be overcome to achieve this understanding.
In the proposed research we will tackle two of the challenges: first, the dynamics of fate choices, i.e. the dependence of transitions on time and inductive signals, remains cryptic; second,…
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