CORDIS Project
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This project focuses on analyzing T-cell receptor repertoires from vaccination participants to predict immune responses. A computational tool will be developed to assess which individuals are likely to have strong immune reactions based solely on their T-cell data.
T-cells are increasingly recognized to be pivotal actors in the development of vaccine-induced immune responses.
Through their T-cell receptor (TCR) on their cell surface, T-cells can recognize antigens derived from pathogens or vaccines.
The strength of the interaction between the TCRs and the vaccine antigens will direct the T-cell dynamics after vaccination.
In this project, we will analyse the TCR repertoires from participants from three distinct vaccination cohorts prior to vaccination and…
UNIVERSITEIT ANTWERPEN
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