CORDIS Project
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This project investigates the formation and regulation of centrioles, which are critical for various cellular structures involved in movement and division. By identifying new molecular components and testing their roles, the research aims to enhance understanding of diseases linked to centriole dysfunction, such as can…
Centrioles are essential for the formation of several microtubule organizing structures including cilia, flagella and centrosomes.
These structures are involved in a variety of functions, from cell motility to division.
Centrosome defects are seen in many cancers, while abnormalities in cilia and flagella can lead to a variety of human diseases, such as polycystic kidney disease.
The molecular mechanisms regulating centriole biogenesis have only recently started to be unravelled, opening new way…
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