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The Mini Brain project develops human-derived 3D cerebral organoids to create realistic models of the human brain for studying neurodegenerative and developmental diseases. These organoids offer a promising alternative to traditional animal models for drug testing and development.
Transferring results from animal models to humans is a major bottleneck in pharmaceutical research.
This is particularly true for brain disorders, including neurodegenerative and developmental diseases.
Both animal models and conventional cell culture methods fail to recapitulate the complexity of the human brain and there are fundamental differences in developmental and physiological aspects between humans and the commonly used animal models.
The high attrition rate of drugs for brain disorders…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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