CORDIS Project
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This project focuses on developing non-invasive methods for screening embryos in In Vitro Fertilisation by analyzing extracellular vesicles released by embryos. It aims to improve embryo selection for implantation without the risks associated with invasive biopsy techniques.
Preimplantation Genetic Screening (PGS) based on high-throughput embryo genome sequencing is currently utilised in In Vitro Fertilisation (IVF) to select for euploid embryos prior to uterine transfer in order to increase implantation potential.
The methodology for the acquisition of genetic material is controversial, as the invasive embryo biopsy required for PGS may compromise embryo quality.
Moreover its long-term biosafety has not been evaluated.
Consequently, the development of non-invasive…
OSPEDALE SAN RAFFAELE SRL
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