CORDIS Project
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This project aims to develop a comprehensive understanding of lipid-targeting antibiotics, which specifically target unique lipids in bacterial membranes. By employing advanced imaging and analytical techniques, the research seeks to elucidate the mechanisms of these antibiotics, potentially leading to new treatments f…
Antimicrobial resistance is a major threat to global health.
To combat this threat, new antibiotics with novel binding modes are urgently needed.
Ideal candidates could be lipid-targeting antibiotics (LT-antibiotics) that target special lipids that only exist in bacterial, but not in human cell membranes.
These drugs kill refractory pathogens without detectable resistance.
This has generated huge interest.
So far, the molecular mechanisms of LT-antibiotics have proven elusive due to technical c…
UNIVERSITEIT UTRECHT
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