CORDIS Project
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This project aims to understand and disrupt hidden reservoirs of the Human Immunodeficiency Virus type 1 (HIV-1) within cells. By studying the dynamics of these reservoirs, it seeks to develop new therapeutic strategies targeting virus persistence.
Human Immunodeficiency Virus type 1 (HIV-1) remains a significant cause of comorbidity and mortality around the world.
One of HIV-1 persistence and immune evasion mechanisms is the ability to create hidden virus reservoirs in cells.
These virus reservoirs, termed Virus-Containing Compartments (VCCs) are inaccessible to the immune system and help to spread the infection to different parts of the body. VCCs are unaffected by current HIV-1 therapies, and thus remain a major obstacle in the developm…
FUNDACIO PRIVADA INSTITUT DE RECERCA SOBRE IMMUNOPATOLOGIES-CAIXA, IRSICAIXA
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