CORDIS Project
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This project explores the genetic and molecular mechanisms behind gut immunocompetence in fruit flies. By integrating regulatory genomics and bioinformatics, it aims to understand how host species adapt to pathogens within their gastrointestinal systems.
The emergence of a gastrointestinal tract within the body cavity is one of the major innovations in animal evolution allowing the transition from an intra- to an extracellular mode of digestion.
With this emergence came the opportunity for infectious agents to exploit this intestinal ecosystem for their own transmission.
Gut-bearing organisms therefore evolved complex mechanisms to defend themselves against these agents, making them “gut immunocompetent”.
This involved a process of continuous ad…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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