CORDIS Project
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This project explores the role of the splicing factor SF2/ASF in cancer development. By examining its function as a proto-oncogene and its influence on alternative splicing, the research aims to uncover new insights into cancer mechanisms and potential therapeutic targets.
Cancer is a multifaceted disease involving numerous mutations in many tumor suppressors and oncogenes.
Elucidation of the molecular basis of cancer has been and continues to be a major goal of biomedical research in the past few decades.
Previous evidence suggests a connection between alternative splicing and cancer, and the activities of many oncogenes and tumor suppressors are modulated by alternative splicing.
We found recently that the splicing factor SF2/ASF is a potent proto-oncogene, capa…
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