CORDIS Project
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This project explores the relationship between genetic variations and phenotypic outcomes, focusing on how genetic interactions shape traits. By conducting large-scale genomic experiments, it aims to enhance our understanding of evolutionary processes and improve predictions of human disease mutations.
The fitness landscape, the representation of how the genotype manifests at the phenotypic (fitness) levels, may be among the most useful concepts in biology with impact on diverse fields, including quantitative genetics, emergence of pathogen resistance, synthetic biology and protein engineering.
While progress in characterizing fitness landscapes has been made, three directions of research in the field remain virtually unexplored: the nature of the genotype to phenotype of standing variation (v…
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
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