CORDIS Project
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This project aims to enhance cancer immunotherapy by developing a multifunctional therapeutic toolbox that targets the tumor microenvironment. It focuses on creating vaccines and immune checkpoint inhibitors to stimulate the immune system while minimizing side effects, ultimately improving treatment outcomes and patien…
Cancer evades the immune system by generating an immunosuppressive tumour-microenvironment through various mechanisms to enable unhampered growth.
Recent breakthroughs in blocking one of these mechanisms – the so called ‘immune checkpoints’ – put cancer immunotherapy back in the spotlights.
Although promising, clinical benefits of these checkpoint inhibitors as single treatment has been limited to a subset of patients and goes along with unwanted systemic autoimmune toxicity. I hypostasize, that…
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
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STICHTING RADBOUD UNIVERSITEIT
Netherlands, Nijmegen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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