CORDIS Project
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This project focuses on developing new methods for the asymmetric introduction of trifluoromethyl groups into organic molecules, specifically targeting carbonyl compounds. By creating innovative chiral catalysts, the goal is to synthesize optically pure fluorinated products, benefiting the pharmaceutical and agrochemic…
Molecules containing fluorine (F) atoms have very important roles in medicinal chemistry. F atoms impart certain properties to the biological activity of a drug, such as making it easier to absorb by the body (bioavailability), and greater potency (metabolic stability).
On the other hand, being able to produce specific enantiomers (‘mirror images’) of a molecule is also critical, as enantiomers often have very different biological activities.
There is a great need to produce optically active mol…
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