CORDIS Project
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This project aims to understand the import of cytosolic tRNAs into mitochondria in the green alga Chlamydomonas reinhardtii. It will manipulate mitochondrial genomes to study the regulation of tRNA import and the role of specific genes in this process.
During evolution, plant mitochondrial genomes underwent multiple rearrangements leading to the loss of genetic information.
One of the consequences is that the number of mitochondrial encoded tRNA genes is not sufficient to ensure plant mitochondrial translation.
In order to compensate this deficiency, cytosolic tRNAs have to be imported into mitochondria.
Although this phenomenon is an essential process for mitochondrial biogenesis in most eukaryotic cells, it remains poorly understood.
The un…
UNIVERSITE DE LIEGE
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