CORDIS Project
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CholMap focuses on developing a universal sterol-based probe to study cholesterol transport proteins, which are crucial for maintaining cholesterol balance in the body. This innovative tool aims to enhance understanding of these proteins and their role in diseases like cardiovascular issues and cancer.
Cholesterol is a structural component of membranes and plays a key role in human health by regulating the fluidity of membranes and affecting signaling pathways.
Intracellular cholesterol transport proteins (CTP) are responsible for maintaining cholesterol homeostasis by regulating local cholesterol concentrations, arising from de novo biosynthesis or dietary sources.
Dysregulated cholesterol transport is associated with cardiovascular disease but also Alzheimer's and cancer.
Despite the obvious…
TECHNICAL UNIVERSITY OF DENMARK DTU
DANMARKS TEKNISKE UNIVERSITET
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