CORDIS Project
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This project focuses on developing a novel protein-based hydrogel system for treating osteoarthritis by promoting cartilage repair. The hydrogels are designed for non-surgical application, providing mechanical support and biological cues to facilitate stem cell differentiation into chondrocytes.
Osteoarthritis (OA) is a type of joint disease that results from breakdown of cartilage and subsequent damage to the underlying bone.
Polymeric biomaterials have rapidly expanded to promote cell differentiation and tissue regeneration, and are uniquely placed to provide sophisticated solutions for the treatment of OA.
Among them, hydrophilic, biocompatible 3D networks, called hydrogels, represent the gold standard for tissue regeneration, owing to their high-water content and tuneable mechanical…
THE UNIVERSITY OF BIRMINGHAM
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