CORDIS Project
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This project focuses on understanding how DNA is organized into chromatin and how this structure is restored during DNA replication. By developing a novel technique called nascent chromatin capture, the research aims to uncover mechanisms of chromatin restoration and the effects of replication timing and stress on chro…
Inheritance of DNA sequence and its proper organization into chromatin is fundamental for eukaryotic life.
The challenge of propagating genetic and epigenetic information is met in S phase and entails genome-wide disruption and restoration of chromatin coupled to faithful copying of DNA.
How specific chromatin structures are restored on new DNA and transmitted through mitotic cell division remains a fundamental question in biology central to understand cell fate and identity.Chromatin restoratio…
KOBENHAVNS UNIVERSITET
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