CORDIS Project
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This project aims to understand the mechanisms behind chromosome segregation errors during the maturation of human eggs, which can lead to pregnancy loss and genetic disorders. It combines genetic screening and live cell analysis to explore these processes.
All animal life starts with the fertilization of an egg. A haploid egg and a haploid sperm fuse and together they form a new genetically unique embryo.
But surprisingly, eggs frequently contain an incorrect number of chromosomes.
Depending on the age of the woman, 10-50% of eggs are chromosomally abnormal.
This high percentage of abnormal eggs results from chromosome segregation errors during oocyte maturation, the process by which a diploid oocyte matures into a haploid egg.
Thus, errors during…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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United Kingdom, LONDON
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
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