CORDIS Project
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This project investigates the mechanisms of sister chromatid cohesion during cell division using the yeast model organism Saccharomyces cerevisiae. It aims to understand how the Scc2/Scc4 complex binds to chromosomes and regulates cohesin and condensin loading, which is crucial for accurate chromosome segregation and h…
In eukaryotic cells, cohesion between sister chromatids allows chromosomes to biorient on the metaphase plate and holds them together until they separate into daughter cells at anaphase onset.
Accurate control of the mechanisms implicated in sister chromatids cohesion after DNA replication and chromosome condensation during mitosis are essential for faithful chromosome segregation during cell division.
The aim of this project is to characterise the chromosomal features underlying Scc2/Scc4 bindi…
CANCER RESEARCH UK LBG
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