CORDIS Project
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This project investigates the cellular mechanisms that protect DNA from damage, focusing on the response to double-strand breaks. By employing a novel method to create specific DNA damage in chromatin, it aims to identify new factors involved in DNA repair processes, enhancing our understanding of genomic stability and…
In stark contrast to common belief, cellular DNA is not de facto safe as it constantly encounters numerous perils.
To keep chromosomal DNA intact and to prevent the onset of pathological conditions, such as cancer and premature ageing, which are driven by DNA damage-induced genomic instability, life has evolved appropriate protective mechanisms, collectively referred to as the DNA Damage Response (DDR). A vital branch of the DDR is the response to DNA double-strand breaks (DSBs), arguably the mo…
KOBENHAVNS UNIVERSITET
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