CORDIS Project
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The CIRCOMMUNICATION project focuses on understanding circadian clocks and their impact on human health, particularly in drug efficacy and side effects. It developed CircaSCOPE, a high-throughput method for constructing Phase Transition Curves, which aids in identifying clock-modulating drugs for better therapeutic out…
Circadian clocks carry an immense importance to human health, as clock disruption is related to various malignancies from sleep disorders through diabetes to cancer.
Furthermore, many drug targets are influenced by circadian clocks.
In order to maximize drugs efficacy while minimizing side effects, it is necessary to consider the drugs time-of-administration, also known as chronotherapy.
These revelations are critical for drug administration and development.
However, their practical implementati…
WEIZMANN INSTITUTE OF SCIENCE
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