CORDIS Project
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This project investigates the mechanisms of cilia formation, focusing on the intraflagellar transport complex that delivers essential building blocks. By employing advanced biochemical and structural biology techniques, the research aims to clarify how tubulin is recruited for cilium assembly, contributing to our under…
Cilia are essential hair-like structures presented at the surface of eukaryotic cells that allow motility, fluid flow and complex inter- and intracellular signalling events.
Nine pairs of microtubules organized in a cylindrical shape called axoneme form the backbone of cilia.
The formation and maintenance of cilia is dependent on a multi-subunit protein complex termed the intraflagellar transport (IFT) complex that actively delivers axonemal building blocks such as tubulin from the base to the t…
AARHUS UNIVERSITET
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