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The CLATHPOL project investigates the formation of Clathrin Coat Vesicles by examining the biochemical and physical factors that influence clathrin polymerization and membrane shape. It employs advanced microscopy techniques to study the dynamics of coat assembly and the forces exerted on membranes during this process.
The “CLATHPOL” project focuses upon a fundamental aspect of Clathrin Coat Vesicle formation.
The critical biochemical (clathrin/adaptor interactions, membrane composition) and physical parameters (deformation forces, role of pre-induced curvature) controlling the shape and polymerization rate of clathrin coats will be determined and the forces applied on the membrane by clathrin polymerization will be measured.
The “CLATHPOL” project will investigate the complex interactions driving clathrin coa…
UNIVERSITE DE GENEVE
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