CORDIS Project
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This project aims to develop a compact fluorescence correlation spectroscopy system that utilizes hollow-core optical waveguides for detecting nanoscale species. The innovative design enhances observation times and detection speed, making it suitable for clinical and research applications.
Fluorescence correlation spectroscopy (FCS) is an innovative technique for the detection and characterization of nanoscale species within their natural environment.
It has successfully measured protein-protein and protein-lipid interaction dynamics, determined spectroscopic parameters of fluorophores and monitored binding constants among diffusing species.
However, current FCS systems, predominantly based on confocal microscopes, have large footprint and inflexible focal observation volumes, lim…
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