CORDIS Project
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This research aims to explore the clonal and cellular diversity of breast cancer and how it evolves during treatment. By analyzing tumor samples over time, the project seeks to uncover new insights into cancer biology and therapy resistance.
CLONAL AND CELLULAR HETEROGENEITY OF BREAST CANCER AND ITS DYNAMIC EVOLUTION WITH TREATMENTBreast cancer remains one of the leading causes of cancer death in women.
One of the greatest challenges is that breast cancer is a heterogeneous group of 10 diseases defined by genomic profiling.
In addition, each tumor is composed of clones and clonal evolution underpins the successive acquisition of the hallmarks of cancer, including metastasis and resistance to therapy.
Furthermore tumors display biolo…
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