CORDIS Project
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This project investigates the mechanisms of horizontal gene transfer in Vibrio cholerae, a bacterium responsible for cholera. It focuses on understanding how this pathogen takes up DNA from its environment, which is crucial for its evolution and antibiotic resistance.
Horizontal gene transfer (HGT) allows rapid bacterial evolution including the spread of genes encoding antibiotic resistance and virulence factors.
The Gram-negative bacterium Vibrio cholerae is an important human pathogen that causes the pandemic disease Cholera.
In its natural aquatic environment growth on the chitinous exoskeletons of zooplankton initiates the development of ‘Natural Competence’, a widespread and key form of HGT that allows bacteria to take up free DNA from the environment. D…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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