CORDIS Project
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This project investigates the role of adaptor protein-2 in regulating clathrin-mediated endocytosis, a process vital for cellular function. By employing advanced molecular techniques, the research aims to uncover how specific protein interactions influence the early stages of endocytosis, which is crucial for maintaini…
The plasma membrane represents the interface between cells and their neighborhood, mediating diverse processes such as cell–cell communication, cell–matrix interactions and uptake of nutrients.
As a result, clathrin mediated endocytosis (CME) has a central role in maintaining cellular homeostasis and function and mis-regulation of endocytic traffic is linked to many human diseases.
Yet, the mechanisms regulating CME remain poorly understood.
We aim to define the role(s) of the adaptor protein-2…
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