CORDIS Project
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This project investigates the mechanisms that maintain the integrity of the endothelial barrier in the brain, particularly during cerebral malaria. By combining advanced experimental methods with mathematical modeling, it aims to enhance understanding of endothelial dysfunction and inform potential therapeutic strategi…
The integrity of the endothelial barrier is vital for maintaining healthy brain function and is especially compromised in pathological conditions such as cerebral malaria.
Despite its significance, the current understanding of the mechano-chemical mechanisms operating at sub-cellular, inter-cellular, and tissue scales within endothelial barriers during cerebral malaria remains limited.
This project aims to close this knowledge gap by integrating advanced in vitro experimental methods with multi-…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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