CORDIS Project
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This project examines the relationship between metabolism and inflammation in chronic viral hepatitis. It aims to identify how these processes interact and influence tissue damage using advanced technologies to map molecular changes over time.
Inflammation is a response to noxious stimuli and initiates tissue repair.
If resolution fails, however, chronic inflammation develops, which drives tissue damage in many diseases including autoimmunity, cancer and infections.
Inflammatory processes are increasingly being appreciated as tightly integrated with metabolic pathways.
The molecular crosstalk occurs on different levels including secreted metabolites and cytokines. I hypothesise that this interface of metabolism and inflammation repres…
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