CORDIS Project
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This project explores how obesity affects insulin resistance in the brain, particularly in the Dorsal Vagal Complex. By studying molecular mechanisms, it aims to identify potential targets for new treatments to combat obesity and diabetes.
The central nervous system (CNS) integrates peripheral hormonal signals to regulate glucose homeostasis and feeding behavior.
Obesity can cause the development of insulin resistance in the brain and completely disrupt the regulative functions of the CNS.
Restoring the brain’s ability to modulate metabolic functions could be very important to prevent the negative outcomes of obesity and diabetes.
The Dorsal Vagal Complex (DVC) in the brainstem senses insulin to regulate glucose metabolism and fee…
UNIVERSITY OF LEEDS
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