CORDIS Project
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This project investigates the evolutionary origins of immune systems by exploring bacterial defenses against viruses. It aims to identify novel immune proteins and understand how both bacteria and viruses have evolved mechanisms to evade immune responses, ultimately revealing insights into host-pathogen interactions ac…
Across the tree of life, genetic conflicts between hosts and pathogens have fueled the diversification of intracellular defenses that collectively define innate immunity.
While prokaryotic and eukaryotic immunity have long been considered distinct, the recent discoveries of multiple defense systems protecting bacteria against viruses called phages have profoundly challenged this paradigm.
In particular, some components of eukaryotic innate immunity were shown to have a deep evolutionary origin i…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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