CORDIS Project
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This project investigates how thyroid hormones are delivered to the fetal brain, focusing on the role of transporters and the impact of medications taken during pregnancy. It aims to improve fetal health outcomes by understanding these mechanisms.
Adequate supply of thyroid hormones is essential for fetal brain development throughout pregnancy.
Hypothyroid fetuses suffer various postnatal disorders ranging from reduced IQ to mental retardation and spasticity.
Over the past decade, studies on the delivery of thyroid hormones into the fetal brain have focused on the role of placental and fetal uptake transporters, whereas little is known about the mechanisms that control hormone removal from fetal tissues.
This question is clinically releva…
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