CORDIS Project
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This project investigates genetic factors contributing to colorectal cancer susceptibility in families. It employs advanced genomic techniques to identify structural variations in the genome that may influence cancer risk and treatment response, aiming to enhance personalized medicine approaches for colorectal cancer p…
Cancer susceptibility genes involved in Mendelian inherited forms of colorectal cancer (CRC) (e.g., Lynch Syndrome) may account for only 5% of all CRC cases.
However, increased cancer risk because of a positive family history may vary from 25 up to 40%, and the genetic basis for this familial aggregation remains largely unknown.
Recently, high-resolution genomic strategies have revealed an unprecedented form of structural variation of the genome in the normal population, including copy number va…
FUNDACIO DE RECERCA CLINIC BARCELONA-INSTITUT D INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER
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