CORDIS Project
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This project investigates the type VII secretion system in bacteria, particularly in Mycobacterium species. By studying its role in host-pathogen interactions and interbacterial competition, it aims to uncover new strategies for combating infections caused by these pathogens.
Bacteria interact with their environment via specialised secretion systems that deliver proteins outside of the cell.
Due to a bias in research efforts, for many years such systems were assumed to be unique to Gram-negative bacteria. A major exception is the type VII secretion system (T7SS), which is widespread in Gram-positive bacteria and actinobacteria, including the important human pathogen Mycobacterium tuberculosis.
The T7SS is a complex secretion apparatus that exports folded proteins and…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Germany, Hamburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Newcastle Upon Tyne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Switzerland, Lausanne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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