CORDIS Project
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This project focuses on understanding the structure and function of (endo)lysins, enzymes that target bacterial cell walls, as potential alternatives to antibiotics. By employing advanced computational methods, it aims to create synthetic lysins and establish a testing platform to enhance their therapeutic applications…
(Endo)lysins are phage-encoded enzymes that degrade the peptidoglycan layer of bacterial cell walls, facilitating the release of viral progeny.
Both wild-type and engineered lysins have shown promise as alternatives or complements to antibiotics, of importance in light of rising antimicrobial resistance.
However, current lysin research and development (R&D) efforts remain largely empirical, needing resource-intensive screening processes that often yield limited generalizable insights.
This chall…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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Belgium, Gent
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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