CORDIS Project
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This project investigates how multiple guidance cues influence the migration of embryonic neurons and axons, focusing on a specific protein super-complex. By elucidating its structure and function, the research aims to enhance understanding of neuronal circuit formation, which is crucial for brain development.
Brain development relies on formation of functional neuronal circuits.
This requires coordinated migration of embryonic neurons and their cellular processes such as axons to the target regions and their selective connections with synaptic partners.
The migration of neurons and axons is mediated by guidance cues.
Combined interactions of multiple guidance cues with their receptors direct neurons and axons to their final destinations.
So far our understating is limited to the effect of individual…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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