CORDIS Project
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This research focuses on the bacterium Treponema pallidum, which causes syphilis, utilizing a new in vitro culture model to study its gene expression. The project aims to uncover the pathogen's biology and interactions with host cells, potentially informing future treatments and understanding of the disease.
Syphilis, caused by the bacterium Treponema pallidum subsp. pallidum (TPA) is considered a re-emerging disease with over 5.6 million cases worldwide.
Despite causing severe life-threatening infections, very little is known about the basic biology and pathogenesis of TPA, largely as the result of the inability to routinely propagate it in vitro.
The recently described in vitro culture model (containing rabbit epithelial cells) has opened new avenues for the study of the basic biology of this path…
GENOME RESEARCH LIMITED
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