CORDIS Project
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This project focuses on developing a versatile synthetic method to create complex natural products, including tricyclic compounds, from a common precursor. The approach aims to simplify access to various biologically significant molecules and potential therapeutic agents through controlled chemical reactions.
A general and highly efficient diversity-oriented synthesis of tricyclic angularly fused-structured natural products, such as arteannuins, alliacanes, pentalenolactones and triquinanes, via selective cyclization from a common precursor is
proposed.The outlined synthetic methodology offers conceptually novel perspective, enabling to deliver multiple targets via cascade sequence of controlled intramolecular reactions from a common easily accessible key precursor; thus,
providing simplified access…
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