CORDIS Project
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This project focuses on developing engineered bacteria to produce and export neuroactive peptides from cone snail venom. By utilizing a specialized secretion system, it aims to rapidly purify and characterize novel toxins for potential neurobiological applications.
Toxins occur in a broad diversity in nature and are produced by a wide array of organisms, including spiders, snails, or plants.
Conotoxins are a class of toxins that are synthesized in the venom duct of the marine cone snail, genus Conus.
The venom of each Conus species is composed of 100 different toxins that rapidly affect the prey organism at multiple targets.
The majority of toxins target ligand-gated or voltage-gated ion channels.
Each neuroactive peptide of the venom is highly specific fo…
UNIVERSITE DE FRIBOURG
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