CORDIS Project
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This project aims to enhance photodynamic therapy by developing new photosensitizers that release reactive oxygen species over time. This innovative approach seeks to improve treatment efficacy for cancer while minimizing side effects associated with traditional light exposure.
Photodynamic therapy is a form of phototherapy which uses light-sensitive compounds (photosensitizers) that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells.
The photosensitizer creates a highly reactive singlet oxygen species which rapidly reacts with any nearby biomolecules leading to destructive reactions resulting in cell death through apoptosis or necrosis.
However, prolonged exposure of tissue to light irradiation causes photosens…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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