CORDIS Project
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The project aims to investigate the interactions between breast cancer cells and bone cells, specifically osteocytes, to understand the mechanisms behind metastatic bone disease. By mapping the osteocyte networks at the tumor-bone interface, it seeks to identify new therapeutic targets for improving treatment outcomes…
Metastatic breast cancer claims the lives of more European women than any other cancer, and is an ever-growing problem in an aging global population that increasingly survives treatment of primary cancer.
The most common site for metastatic breast lesions is bone, with 75% of patients experiencing pathological fractures, spinal cord compression or severe bone pain.
Crosstalk between cancer cells and osteocytes, which make up more than 90% of our bone cells and form a complex sensing and signalli…
QUEEN MARY UNIVERSITY OF LONDON
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