CORDIS Project
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This project investigates how the shape of epithelial cells is regulated during the metamorphosis of Drosophila. By examining the peripodial membrane, it aims to understand the cellular dynamics and factors involved in this morphological process.
I propose to analyze how epithelial cell shape is controlled, using the Drosophila peripodial membrane as a model system.
Drosophila third instar imaginal discs are a composed of two contiguous layers of cells of distinct morphology: a pseudostratified one, called the proper epithelium (PE), and a squamous epithelium, the peripodial membrane (PM).
While the PE has been deeply studied, little is known about the PM.
The peripodial membrane has the ability to change its shape in response to ecdyson…
MEDICAL RESEARCH COUNCIL
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