CORDIS Project
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This research investigates how growth and patterning in animals are coordinated, focusing on the Dpp protein's role in transcriptional regulation. By studying Drosophila, the project aims to understand the dynamics of Dpp signaling and its implications for developmental biology.
Animals and their organs become patterned as they grow.
One of the most intriguing and challenging questions in developmental biology today is how patterning and growth are coordinated in time and space.
Dpp, a member of TGF-β superfamily, with its ability to regulate both processes, serves as a paradigm to answer this question.
Our first aim focuses on the logic of transcriptional regulation by Smad proteins, the nuclear effectors of the TGF-β pathways.
The Drosophila Smad proteins, Mad and Med…
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