CORDIS Project
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Cor-Edit-P aims to develop a gene therapy for genetic cardiomyopathy using Crispr-Cas9 technology in pigs. By creating porcine models and applying targeted gene editing, the project seeks to improve heart function and quality of life for patients with dilated cardiomyopathy caused by specific genetic mutations.
Heart failure represents a common cause of death in European societies and is frequently based on dilated cardiomyopathy (DCM) which might be caused by mutations in cardiomyocyte genes.
While no specific treatment exists, new therapeutic options are a major unmet clinical need.As attractive novel key approach, Cor-Edit-P will use Crispr-Cas9 based gene editing for distinct gene therapy of genetic cardiomyopathy, using pigs as a unique, clinic-related large animal model system.
My lab tailored hi…
KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
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