CORDIS Project
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This research focuses on understanding the cortical dysfunctions that lead to L-DOPA-induced dyskinesias in Parkinson's disease patients. By using a combination of brain stimulation techniques and clinical evaluations, it aims to identify markers that could predict the risk of developing these complications.
Parkinson’s disease (PD) is a neurodegenerative disorder that affects about 1% of the population over 55.
After more than 50 years, dopaminergic treatment is still the gold standard in PD therapy, although, as the disease progresses, several motor complications may arise.
One of the most common and debilitating are known as L-DOPA-induced dyskinesias (LIDs), a condition that is observed in up to 80% of patients within five years of L-DOPA or dopaminergic agonists treatment.
Although the exact ne…
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