CORDIS Project
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This project investigates how coronaviruses attach to cell surfaces, focusing on the interactions between viral spike proteins and cellular receptors. By studying different coronaviruses, it aims to understand the factors influencing the severity of infections and enhance knowledge in virology and biophysics.
Coronaviruses (CoV) have been responsible for several severe viral outbreaks culminating in the current global pandemic.
However, some viruses of this family are widespread and only cause mild conditions, like the common cold.
The origin of the significant variation in the severity of the CoV-related diseases is still poorly understood.
Recent studies have suggested that the strength of the interaction between the virus and the cell surface during the early stages of virus entry could play an im…
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